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H3D: Drug Discovery & Development

UNIVERSITY OF CAPE TOWN » Faculty of Science

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Adam, Yassir Dr

Akester, Jessica Miss

Akester, Jessica Miss

Arendse, Lauren Dr

Basarab, Gregory Steven Dr

Publications

2-Mercapto-quinazolinones as inhibitors of type II NADH dehydrogenase and mycobacterium tuberculosis: structure-activity relationships, mechanism of action and absorption, distribution, metabolism, and excretion characterization (2018)

4-Aminoquinoline antimalarials containing a benzylmethylpyridylmethylamine group are active against drug resistant Plasmodium falciparum and exhibit oral activity in mice (2017)

Antibacterial FabH Inhibitors with Mode of Action Validated in Haemophilus influenzae by in Vitro Resistance Mutation Mapping (2016)

Antimalarial efficacy of MMV390048, an inhibitor of plasmodium phosphatidylinositol 4-kinase (2017)

Antimalarial lead-optimization studies on a 2,6-imidazopyridine series within a constrained chemical space to circumvent atypical dose-response curves against multidrug resistant parasite strains (2018)

Contact Details

Address: Cape Town