Journal article

Developing Country Applications of Molecular Farming: Case Studies in South Africa and Argentina

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Publication Details

Author list: Rybicki EP, Hitzeroth II, Meyers A, Santos MJD, Wigdorovitz A

Publisher: Bentham Science Publishers

Publication year: 2013

Journal: Current Pharmaceutical Design

Journal name: Current Pharmaceutical Design

Volume number: 19

Issue number: 31

Start page: 5612

End page: 5621

Total number of pages: 10

ISSN: 1381-6128

URL: http://www.scopus.com/inward/record.url?eid=2-s2.0-84874073920{&}partnerID=40{&}md5=77c31140a2b9c9c7b95b3fe7d050d2d7


Abstract

Molecular farming is a technology that is very well suited to being applied in developing countries, given the reasonably high level of expertise in recombinant plant development in many centers. In addition, there is an urgent need for products such as inexpensive vaccines and therapeutics for livestock and for some human diseases - and especially those that do not occur or are rare in developed regions. South Africa and Argentina have been at the fore in this area among developing nations, as researchers have been able to use plants to produce experimental therapeutics such as nanoantibodies against rotavirus and vaccines against a wide variety of diseases, including Rabbit haemorrhagic disease virus, Foot and mouth disease virus, Bovine viral diarrhoea virus, bovine rotaviruses, Newcastle disease virus, rabbit and human papillomaviruses, Bluetongue virus, and Beak and feather disease virus of psittacines. A combination of fortuitous scientific expertise in both places, coupled with association with veterinary and human disease research centers, has enabled the growth of research groups that have managed to compete successfully with others in Europe and the USA and elsewhere, to advance this field. This review will cover relevant work from both South Africa and Argentina, as well as a discussion about the perspectives in this field for developing nations.


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Keywords

Vaccines


Last updated on 2019-05-04 at 11:06